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Inflammation and Immune Response in Chronic Disease

NURS 1097: Pathophysiology for Nurses – Discussion Board Assignment 1

Overview

This discussion activity is designed to encourage critical analysis of disease processes through collaborative learning. Students will explore the relationship between pathophysiological mechanisms, clinical signs, and nursing care strategies. Each student is expected to contribute thoughtfully to the discussion and demonstrate understanding of evidence-based practice in pathophysiology.

Discussion Topic

Topic: Inflammation and Immune Response in Chronic Disease Management

Discuss the physiological role of inflammation in chronic disease progression. Choose one chronic condition (e.g., rheumatoid arthritis, inflammatory bowel disease, or asthma) and explain how dysregulated immune and inflammatory responses contribute to the development and complications of the disease. Support your discussion with recent peer-reviewed evidence.

Discussion Instructions

  1. Initial Post (Due by Week 4)
    • Write 300–400 words addressing the discussion question.
    • Use at least two current peer-reviewed references (published between 2019–2025).
    • Apply pathophysiological concepts to explain clinical features and nursing implications.
    • Integrate evidence-based sources using APA 7th referencing.
  2. Peer Responses (Due by Week 5)
    • Respond to at least two peers’ posts (minimum 150 words each).
    • Extend the discussion by adding new perspectives or clarifications supported by literature.
    • Be professional and constructive in your feedback.

Assessment Rubric Criteria

  1. Knowledge Application (30%) – Demonstrates understanding of pathophysiological mechanisms relevant to the chosen disease.
  2. Critical Thinking (25%) – Connects inflammation and immune responses to clinical outcomes and nursing care.
  3. Evidence Integration (25%) – Uses credible, recent research to support analysis and discussion points.
  4. Engagement and Interaction (10%) – Provides meaningful peer responses that contribute to collaborative learning.
  5. Academic Writing and Referencing (10%) – Maintains academic tone, coherence, and accurate APA 7th formatting.

Learning Outcomes

  • Understand the biological mechanisms of inflammation and immune regulation.
  • Apply pathophysiological principles to chronic disease management.
  • Demonstrate evidence-based reasoning in nursing discussions.

This 2025 NURS 1097 discussion board post assignment aligns with updated nursing education standards emphasizing collaborative analysis and application of pathophysiology in chronic disease management. It reflects real discussion assessment formats used in North American and Australian nursing programs for improved academic engagement and critical reasoning development.

 References

  1. Huether, S. E., McCance, K. L. & Brashers, V. L. (2023). Understanding Pathophysiology (8th ed.). Elsevier. https://doi.org/10.1016/C2021-0-01769-3
  2. Porth, C. M. & Matfin, G. (2021). Pathophysiology: Concepts of Altered Health States (11th ed.). Wolters Kluwer. https://doi.org/10.1097/9781975172544
  3. Abbas, A. K. & Lichtman, A. H. (2022). Cellular and Molecular Immunology (10th ed.). Elsevier. https://doi.org/10.1016/C2021-0-00089-0
  4. Parrillo, J. E. & Dellinger, R. P. (2020). Critical Care Medicine: Principles of Diagnosis and Management in the Adult (6th ed.). Elsevier. https://doi.org/10.1016/C2017-0-02978-5
  5. Ridley, S. C. & Gillett, R. (2019). “The immune response and chronic inflammation in disease.” Australian Nursing and Midwifery Journal, 26(8), 42–46. https://anmj.org.au

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